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At least 50 people have been killed after a lone gunman opened fire from a hotel window in Las Vegas.

Local authorities expect death toll to rise.

Local law enforcement officers have increased the official number of injured to over 400, as area hospitals continue to treat victims.

50 people are confirmed to have lost their lives after a lone gunman opened fire from the Mandalay Bay hotel. Stephen Paddock shot indiscriminately from the 32nd floor of the hotel, hitting concert goers.

The victims were attending a country music festival in Las Vegas.

According to police, who confirmed that the gunman took his own life as the police raided the hotel room, an arsenal of automatic weapons were found.

Former President Barack Obama tweeted on Monday morning; "Michelle & I are praying for the victims in Las Vegas. Our thoughts are with their families & everyone enduring another senseless tragedy."

The shooting is the deadliest mass shooting event in US history.

The Las Vegas Metro Police Department have issued an emergency number for those concerned about relatives and friends: (866) 535 5654.